Combined effects of glycan chain length and linkage type on the immunogenicity of glycoconjugate vaccines

Abstract The development and use of antibacterial glycoconjugate vaccines have significantly reduced the occurrence of potentially fatal childhood and adult diseases such as bacteremia, bacterial meningitis, and pneumonia. In these vaccines, the covalent linkage of bacterial glycans to carrier prote...

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Bibliographic Details
Main Authors: Chakkumkal Anish, Michel Beurret, Jan Poolman
Format: Article
Language:English
Published: Nature Portfolio 2021-12-01
Series:npj Vaccines
Online Access:https://doi.org/10.1038/s41541-021-00409-1