Combined effects of glycan chain length and linkage type on the immunogenicity of glycoconjugate vaccines
Abstract The development and use of antibacterial glycoconjugate vaccines have significantly reduced the occurrence of potentially fatal childhood and adult diseases such as bacteremia, bacterial meningitis, and pneumonia. In these vaccines, the covalent linkage of bacterial glycans to carrier prote...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
Nature Portfolio
2021-12-01
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Series: | npj Vaccines |
Online Access: | https://doi.org/10.1038/s41541-021-00409-1 |