Association of Neisseria gonorrhoeae Opa(CEA) with dendritic cells suppresses their ability to elicit an HIV-1-specific T cell memory response.

Association of Neisseria gonorrhoeae Opa(CEA) with dendritic cells suppresses their ability to elicit an HIV-1-specific T cell memory response.

Infection with Neisseria gonorrhoeae (N. gonorrhoeae) can trigger an intense local inflammatory response at the site of infection, yet there is little specific immune response or development of immune memory. Gonococcal surface epitopes are known to undergo antigenic variation; however, this is unli...

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Bibliographic Details
Main Authors: Qigui Yu, Edith M C Chow, Shannon E McCaw, Ningjie Hu, Daniel Byrd, Tohti Amet, Sishun Hu, Mario A Ostrowski, Scott D Gray-Owen
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3570455?pdf=render

Internet

http://europepmc.org/articles/PMC3570455?pdf=render

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