CREB3L1 promotes tumor growth and metastasis of anaplastic thyroid carcinoma by remodeling the tumor microenvironment

CREB3L1 promotes tumor growth and metastasis of anaplastic thyroid carcinoma by remodeling the tumor microenvironment

Abstract Anaplastic thyroid carcinoma (ATC) is an extremely malignant type of endocrine cancer frequently accompanied by extrathyroidal extension or metastasis through mechanisms that remain elusive. We screened for the CREB3 transcription-factor family in a large cohort, consisting of four microarr...

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Bibliographic Details
Main Authors: Zongfu Pan, Tong Xu, Lisha Bao, Xiaoping Hu, Tiefeng Jin, Jinming Chen, Jianqiang Chen, Yangyang Qian, Xixuan Lu, Lu li, Guowan Zheng, Yiwen Zhang, Xiaozhou Zou, Feifeng Song, Chuanming Zheng, Liehao Jiang, Jiafeng Wang, Zhuo Tan, Ping Huang, Minghua Ge
Format: Article
Language:English
Published: BMC 2022-10-01
Series:Molecular Cancer
Subjects:
Anaplastic thyroid carcinoma
CREB3L1
Collagen
Extracellular matrix
Cancer-associated fibroblasts
Online Access:https://doi.org/10.1186/s12943-022-01658-x

Internet

https://doi.org/10.1186/s12943-022-01658-x

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