Nr4a1-dependent non-classical monocytes are important for macrophage-mediated wound healing in the large intestine

Nr4a1-dependent non-classical monocytes are important for macrophage-mediated wound healing in the large intestine

IntroductionMacrophages play an important role in intestinal wound healing. However, the trajectories from circulating monocytes to gut macrophages are incompletely understood.MethodsTaking advantage of mice depleted for non-classical monocytes due to deficiency for the transcription factor Nr4a1, w...

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Bibliographic Details
Main Authors: Karin Heidbreder, Katrin Sommer, Maximilian Wiendl, Tanja M. Müller, Imke Atreya, Kai Hildner, Markus F. Neurath, Sebastian Zundler
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-01-01
Series:Frontiers in Immunology
Subjects:
Nr4a1 (Nur77)
monocytes
macrophages
intestinal wound healing
gut homing
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2022.1040775/full

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https://www.frontiersin.org/articles/10.3389/fimmu.2022.1040775/full

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