Systematic Evaluation of Voriconazole Pharmacokinetic Models without Pharmacogenetic Information for Bayesian Forecasting in Critically Ill Patients

Voriconazole (VRC) is used as first line antifungal agent against invasive aspergillosis. Model-based approaches might optimize VRC therapy. This study aimed to investigate the predictive performance of pharmacokinetic models of VRC without pharmacogenetic information for their suitability for model...

Full description

Bibliographic Details
Main Authors: Simon Kallee, Christina Scharf, Lea Marie Schatz, Michael Paal, Michael Vogeser, Michael Irlbeck, Johannes Zander, Michael Zoller, Uwe Liebchen
Format: Article
Language:English
Published: MDPI AG 2022-09-01
Series:Pharmaceutics
Subjects:
Online Access:https://www.mdpi.com/1999-4923/14/9/1920