Role and mechanism of DNase 2α in hypoxia-induced proliferation of rat pulmonary artery smooth muscle cells

Role and mechanism of DNase 2α in hypoxia-induced proliferation of rat pulmonary artery smooth muscle cells

Objective To explore the role and mechanism of DNase 2α on hypoxia-induced proliferation of rat pulmonary artery smooth muscle cells (RPASMCs). Methods Primary RPASMCs were cultured with 3%O2 to establish a hypoxia-induced cell proliferation model. Small interference RNA (siRNA) was used to decrease...

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Bibliographic Details
Main Authors: GENG Jianhui, CHEN Jian, ZHANG Erlong, YANG Yidong
Format: Article
Language:zho
Published: Editorial Office of Journal of Third Military Medical University 2022-04-01
Series:Di-san junyi daxue xuebao
Subjects:
dnase 2α
mitochondrial dna
rat pulmonary artery smooth muscle cells
hypoxia
proliferation
Online Access:http://aammt.tmmu.edu.cn/Upload/rhtml/202111203.htm

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http://aammt.tmmu.edu.cn/Upload/rhtml/202111203.htm

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