Understanding Retinoblastoma Post-Translational Regulation for the Design of Targeted Cancer Therapies

The retinoblastoma protein (Rb1) is a prototypical tumor suppressor protein whose role was described more than 40 years ago. Together with p107 (also known as RBL1) and p130 (also known as RBL2), the Rb1 belongs to a family of structurally and functionally similar proteins that inhibits cell cycle p...

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Bibliographic Details
Main Authors: Radoslav Janostiak, Ariadna Torres-Sanchez, Francesc Posas, Eulàlia de Nadal
Format: Article
Language:English
Published: MDPI AG 2022-02-01
Series:Cancers
Subjects:
Online Access:https://www.mdpi.com/2072-6694/14/5/1265