Platycodin D restores the intestinal mechanicalbarrier by reducing endoplasmic reticulum stress-mediated apoptosis

Platycodin D restores the intestinal mechanicalbarrier by reducing endoplasmic reticulum stress-mediated apoptosis

The current study aimed to reveal the inhibitory effect of Platycodin D (PD) on intestinal cell apoptosis mediated by ER stress. Treatment with PD alleviated pathological changes of the intestine and reduced secretion of intracellular enzyme Diamine oxidase (DAO) in the upper villi of the small inte...

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Bibliographic Details
Main Authors: Mei-ling Fan, Kun Wei, Xiao-meng Wei, Jun-jie Zhang, Jin-gang Hou, Qiong Shen, Yin-shi Sun, Xin-dian Li, Zi Wang, Li-li Jiao, Wei Li
Format: Article
Language:English
Published: Elsevier 2022-12-01
Series:Journal of Functional Foods
Subjects:
Platycodin D
Endoplasmic reticulum stress
Cisplatin
Intestinal mechanical barrier
4-PBA
Intestinal injury
Online Access:http://www.sciencedirect.com/science/article/pii/S1756464622004066

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http://www.sciencedirect.com/science/article/pii/S1756464622004066

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