Free drug percentage of moxidectin declines with increasing concentrations in the serum of marsupials

Moxidectin (MOX) is a macrocyclic lactone used to eliminate endo and ectoparasites in many mammalian species. It is notably the active ingredient of the anti-parasitic drug Cydectin®, manufactured by Virbac, and is frequently used to treat sarcoptic mange in Australian wildlife. Protein binding play...

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Bibliographic Details
Main Authors: Eliza K. Stott, Shuai Nie, Nicholas A. Williamson, Lee F. Skerratt
Format: Article
Language:English
Published: Elsevier 2024-04-01
Series:International Journal for Parasitology: Parasites and Wildlife
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2213224423001001