Development of an HPLC Method with an ODS Column to Determine Low Levels of Aspartame Diastereomers in Aspartame.

Development of an HPLC Method with an ODS Column to Determine Low Levels of Aspartame Diastereomers in Aspartame.

α-L-Aspartyl-D-phenylalanine methyl ester (L, D-APM) and α-D-aspartyl-L-phenylalanine methyl ester (D, L-APM) are diastereomers of aspartame (N-L-α-Aspartyl-L-phenylalanine-1-methyl ester, L, L-APM). The Joint FAO/WHO Expert Committee on Food Additives has set 0.04 wt% as the maximum permitted level...

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Bibliographic Details
Main Authors: Takashi Ohtsuki, Ryoichiro Nakamura, Satoru Kubo, Akira Otabe, Yoko Oobayashi, Shoko Suzuki, Mika Yoshida, Mitsuya Yoshida, Chiye Tatebe, Kyoko Sato, Hiroshi Akiyama
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4807810?pdf=render

Internet

http://europepmc.org/articles/PMC4807810?pdf=render

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