MYC amplifications are common events in childhood osteosarcoma

MYC amplifications are common events in childhood osteosarcoma

Abstract Osteosarcoma, the most common primary malignant tumour of bone, affects both children and adults. No fundamental biological differences between paediatric and adult osteosarcoma are known. Here, we apply multi‐region whole‐genome sequencing to an index case of a 4‐year‐old child whose aggre...

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Bibliographic Details
Main Authors: Solange De Noon, Jannat Ijaz, Tim HH Coorens, Fernanda Amary, Hongtao Ye, Anna Strobl, Iben Lyskjær, Adrienne M Flanagan, Sam Behjati
Format: Article
Language:English
Published: Wiley 2021-09-01
Series:The Journal of Pathology: Clinical Research
Subjects:
MYC
CCNE1
osteosarcoma
genomics
copy number variants
Online Access:https://doi.org/10.1002/cjp2.219

Internet

https://doi.org/10.1002/cjp2.219

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