Inhibition of CSF1R, a receptor involved in microglia viability, alters behavioral and molecular changes induced by cocaine

Abstract Different data suggest that microglia may participate in the drug addiction process as these cells respond to neurochemical changes induced by the administration of these substances. In order to study the role of microglia in drug abuse, Swiss mice aged 8–9 weeks were treated with the CSF1R...

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Bibliographic Details
Main Authors: Maria Carolina Machado da Silva, Giovanni Freitas Gomes, Heliana de Barros Fernandes, Aristóbolo Mendes da Silva, Antônio Lúcio Teixeira, Fabrício A. Moreira, Aline Silva de Miranda, Antônio Carlos Pinheiro de Oliveira
Format: Article
Language:English
Published: Nature Portfolio 2021-08-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-95059-7