Dibutyl phthalate disrupts glycogen synthase kinase 3α essential for sperm motility

Dibutyl phthalate disrupts glycogen synthase kinase 3α essential for sperm motility

To unravel the toxic mechanism of phthalate ester plasticizer endocrine disruptor in spermatozoa, we examined the effect of dibutyl phthalate (DBP) on the stability and inhibitory phosphorylation of glycogen synthase kinase 3α (GSK3α), a protein kinase crucial for sperm motility in mice. In DBP-trea...

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Bibliographic Details
Main Authors: Seung Hyun Park, Myung Chan Gye
Format: Article
Language:English
Published: Elsevier 2024-02-01
Series:Ecotoxicology and Environmental Safety
Subjects:
Dibutyl phthalate
Inhibitory phosphorylation
Ubiquitination
GSK3
Motility
Mouse spermatozoa
Online Access:http://www.sciencedirect.com/science/article/pii/S0147651324000526

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http://www.sciencedirect.com/science/article/pii/S0147651324000526

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