Understanding gene-lifestyle interaction in obesity: the role of mediation versus moderation

Background: Obesity results from complex interactions between genetic susceptibility to weight gain and poor eating and lifestyle behaviors. The approach that has been traditionally used in genetics to investigate gene-environment/lifestyle interaction in obesity is based on the concept of moderatio...

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Bibliographic Details
Main Authors: Louis Pérusse, Raphaëlle Jacob, Vicky Drapeau, Clare Llewellyn, Benoit J Arsenault, Alexandre Bureau, Marie-Ève Labonté, Angelo Tremblay, Marie-Claude Vohl
Format: Article
Language:English
Published: Karger Publishers 2022-03-01
Series:Lifestyle Genomics
Online Access:https://www.karger.com/Article/FullText/523813