Astroglial S100B Secretion Is Mediated by Ca<sup>2+</sup> Mobilization from Endoplasmic Reticulum: A Study Using Forskolin and DMSO as Secretagogues
S100B, a homodimeric Ca<sup>2+</sup>-binding protein, is produced and secreted by astrocytes, and its extracellular levels have been used as a glial marker in brain damage and neurodegenerative and psychiatric diseases; however, its mechanism of secretion is elusive. We used primary astr...
Main Authors: | , , , , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2023-11-01
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Series: | International Journal of Molecular Sciences |
Subjects: | |
Online Access: | https://www.mdpi.com/1422-0067/24/23/16576 |