NIR-II-driven and glutathione depletion-enhanced hypoxia-irrelevant free radical nanogenerator for combined cancer therapy

NIR-II-driven and glutathione depletion-enhanced hypoxia-irrelevant free radical nanogenerator for combined cancer therapy

Abstract Background Though the combination of photodynamic therapy (PDT) and chemodynamic therapy (CDT) appears to be very attractive in cancer treatment, hypoxia and overproduced glutathione (GSH) in the tumor microenvironment (TME) limit their efficacy for further application. Results In this work...

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Bibliographic Details
Main Authors: Li Zhang, Yadi Fan, Zhe Yang, Mo Yang, Chun-Yuen Wong
Format: Article
Language:English
Published: BMC 2021-09-01
Series:Journal of Nanobiotechnology
Subjects:
Hypoxia-irrelevant
Glutathione-depleting
Hydroxyl radical
NIR-II photothermal therapy
Alkyl radical
Online Access:https://doi.org/10.1186/s12951-021-01003-2

Internet

https://doi.org/10.1186/s12951-021-01003-2

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