Influenza Vaccination Results in Differential Hemagglutinin Stalk-Specific Fc-Mediated Functions in Individuals Living With or Without HIV

Influenza Vaccination Results in Differential Hemagglutinin Stalk-Specific Fc-Mediated Functions in Individuals Living With or Without HIV

Influenza virus hemagglutinin (HA) stalk-specific antibodies have been shown to potently induce Fc-mediated effector functions which are important in protection from disease. In placebo-controlled maternal influenza (MatFlu) vaccination trials of pregnant women living with or without HIV, reduced ri...

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Bibliographic Details
Main Authors: Boitumelo M. Motsoeneng, Nisha Dhar, Marta C. Nunes, Florian Krammer, Shabir A. Madhi, Penny L. Moore, Simone I. Richardson
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-04-01
Series:Frontiers in Immunology
Subjects:
influenza vaccination
Fc effector functions
HIV co-infection
hemagglutinin stalk antibodies
antibody-dependent cellular phagocytosis (ADCP)
antibody-dependent complement deposition (ADCD)
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2022.873191/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2022.873191/full

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