Methylated promoter DNA of CDO1 gene and preoperative serum CA19-9 are prognostic biomarkers in primary extrahepatic cholangiocarcinoma.

BACKGROUND:Promoter DNA methylation of Cysteine dioxygenase type1 (CDO1) gene has been clarified as a molecular diagnostic and prognostic indicator in various human cancers. The aim of this study is to investigate the clinical relevance of CDO1 methylation in primary biliary tract cancer (BTC). METH...

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Main Authors: Shuji Nakamoto, Yusuke Kumamoto, Kazuharu Igarashi, Yoshiki Fujiyama, Nobuyuki Nishizawa, Shigenori Ei, Hiroshi Tajima, Takashi Kaizu, Masahiko Watanabe, Keishi Yamashita
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC6191141?pdf=render