β-hydroxybutyrate impairs bovine oocyte maturation via pyruvate dehydrogenase (PDH) associated energy metabolism abnormality

β-hydroxybutyrate impairs bovine oocyte maturation via pyruvate dehydrogenase (PDH) associated energy metabolism abnormality

Background: Ketosis is one of the most frequent and costly metabolic disorders in high-producing dairy cows, and negatively associated with the health and reproductive performance of bovine. Ketosis is mainly caused by the accumulation of ketone body β-hydroxybutyric acid and its diagnosis is based...

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Bibliographic Details
Main Authors: Kai-Yan Zhang, Jing Guo, Cheng-Lin Zhan, Chong-Shan Yuan, Chang-Guo Min, Zhi-Qiang Li, Hong-Yu Liu, Jun Wang, Jing Zhao, Wen-Fa Lu, Xin Ma
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-08-01
Series:Frontiers in Pharmacology
Subjects:
β-hydroxybutyrate (βHB)
PDH
acetylation modification
oocyte maturation
bovine reproductive performance
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2023.1243243/full

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https://www.frontiersin.org/articles/10.3389/fphar.2023.1243243/full

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