β-hydroxybutyrate impairs bovine oocyte maturation via pyruvate dehydrogenase (PDH) associated energy metabolism abnormality
Background: Ketosis is one of the most frequent and costly metabolic disorders in high-producing dairy cows, and negatively associated with the health and reproductive performance of bovine. Ketosis is mainly caused by the accumulation of ketone body β-hydroxybutyric acid and its diagnosis is based...
Main Authors: | Kai-Yan Zhang, Jing Guo, Cheng-Lin Zhan, Chong-Shan Yuan, Chang-Guo Min, Zhi-Qiang Li, Hong-Yu Liu, Jun Wang, Jing Zhao, Wen-Fa Lu, Xin Ma |
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Format: | Article |
Language: | English |
Published: |
Frontiers Media S.A.
2023-08-01
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Series: | Frontiers in Pharmacology |
Subjects: | |
Online Access: | https://www.frontiersin.org/articles/10.3389/fphar.2023.1243243/full |
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