PINK1-PTEN axis promotes metastasis and chemoresistance in ovarian cancer via non-canonical pathway

PINK1-PTEN axis promotes metastasis and chemoresistance in ovarian cancer via non-canonical pathway

Abstract Background Ovarian cancer is commonly associated with a poor prognosis due to metastasis and chemoresistance. PINK1 (PTEN-induced kinase 1) is a serine/threonine kinase that plays a crucial part in regulating various physiological and pathophysiological processes in cancer cells. Methods Th...

Full description

Bibliographic Details
Main Authors: Fang Zheng, Jiamin Zhong, Kelie Chen, Yu Shi, Fang Wang, Shengchao Wang, Song Tang, Xiaoyu Yuan, Zhangjin Shen, Sangsang Tang, Dajing Xia, Yihua Wu, Weiguo Lu
Format: Article
Language:English
Published: BMC 2023-11-01
Series:Journal of Experimental & Clinical Cancer Research
Subjects:
Ovarian cancer
Chemoresistance
Metastasis
Phosphorylation
PINK1
PTEN
Online Access:https://doi.org/10.1186/s13046-023-02823-w

Internet

https://doi.org/10.1186/s13046-023-02823-w

Similar Items