Joint masking and self-supervised strategies for inferring small molecule-miRNA associations

Joint masking and self-supervised strategies for inferring small molecule-miRNA associations

Inferring small molecule-miRNA associations (MMAs) is crucial for revealing the intricacies of biological processes and disease mechanisms. Deep learning, renowned for its exceptional speed and accuracy, is extensively used for predicting MMAs. However, given their heavy reliance on data, inaccuraci...

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Bibliographic Details
Main Authors: Zhecheng Zhou, Linlin Zhuo, Xiangzheng Fu, Juan Lv, Quan Zou, Ren Qi
Format: Article
Language:English
Published: Elsevier 2024-03-01
Series:Molecular Therapy: Nucleic Acids
Subjects:
MT: Bioinformatics
decoder based on node degree
graph masked autoencoder
self-supervised strategy
probability distribution-based masking strategy
small-molecule-miRNA associations
Online Access:http://www.sciencedirect.com/science/article/pii/S2162253123003219

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http://www.sciencedirect.com/science/article/pii/S2162253123003219

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