Exploring the Effect of PAK Inhibition in a 3D Pancreatic Cancer Invasion Model

Pancreatic Ductal Adenocarcinoma (PDAC) is an aggressive cancer, with over half of patients presenting with metastatic PDAC at diagnosis. Most patients receive conventional chemotherapy which invariably faces resistance, and a key facilitator in this is the PDAC stroma which acts as a functional med...

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Bibliographic Details
Main Authors: Marianne Best, Debashis Sarker, Claire M. Wells
Format: Article
Language:English
Published: MDPI AG 2023-04-01
Series:Biology and Life Sciences Forum
Subjects:
Online Access:https://www.mdpi.com/2673-9976/21/1/32