Protective effects of baicalin against L-glutamate-induced oxidative damage in HT-22 cells by inhibiting NLRP3 inflammasome activation via Nrf2/HO-1 signaling

Objective(s): To explore the ability and underlying molecular mechanisms involved in the protective effects of Baicalin (BA) against L-Glutamate-induced mouse hippocampal neuron cell line HT-22.Materials and Methods: The cell injury model of HT-22 cells was induced by L-glutamate, and cell viability...

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Bibliographic Details
Main Authors: Junyuan Li, Gang Wang, Yehao Zhang, Xiaodi Fan, Mingjiang Yao
Format: Article
Language:English
Published: Mashhad University of Medical Sciences 2023-03-01
Series:Iranian Journal of Basic Medical Sciences
Subjects:
Online Access:https://ijbms.mums.ac.ir/article_21727_b1363ec02e365358aed712fb3c428787.pdf