TBX21 predicts prognosis of patients and drives cancer stem cell maintenance via the TBX21–IL-4 pathway in lung adenocarcinoma

TBX21 predicts prognosis of patients and drives cancer stem cell maintenance via the TBX21–IL-4 pathway in lung adenocarcinoma

Abstract Background The Th1 cell-specific transcription factor TBX21 functions as a regulator of expression of a Th1 cytokine, interferon gamma (IFN-γ). However, the specific function of TBX21 correlated with cancer stemness remains unclear. Methods Using univariate and multivariate survival analysi...

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Bibliographic Details
Main Authors: Shuangtao Zhao, Wenzhi Shen, Jiangyong Yu, Luhua Wang
Format: Article
Language:English
Published: BMC 2018-04-01
Series:Stem Cell Research & Therapy
Subjects:
Lung adenocarcinoma
TBX21
Prognosis
Cancer stemness
IL-4
Online Access:http://link.springer.com/article/10.1186/s13287-018-0820-6

Internet

http://link.springer.com/article/10.1186/s13287-018-0820-6

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