miR-544 promotes maturity and antioxidation of stem cell-derived endothelial like cells by regulating the YY1/TET2 signalling axis

miR-544 promotes maturity and antioxidation of stem cell-derived endothelial like cells by regulating the YY1/TET2 signalling axis

Abstract Background Inflammation and oxidative stress induced by oxidized low density lipoprotein are the main causes of vascular endothelial injury and atherosclerosis. Endothelial cells are important for the formation and repair of blood vessels. However, the detailed mechanism underlying the regu...

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Bibliographic Details
Main Authors: Jianming Guo, Qiuling Xiang, Yaojie Xin, Yongyi Huang, Gang Zou, Te Liu
Format: Article
Language:English
Published: BMC 2020-03-01
Series:Cell Communication and Signaling
Subjects:
Induced endothelial cell-like cells
Human amniotic epithelial cells
Epigenetics modification
Antioxidation
Cell therapy
Translational medicine
Online Access:http://link.springer.com/article/10.1186/s12964-019-0504-6

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http://link.springer.com/article/10.1186/s12964-019-0504-6

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