Synthesis of Novel Aryl(heteroaryl)sulfonyl Ureas of Possible Biological Interest

The course of reaction of aryl and heteroaryl sulfonamides with diphenylcarbonate (DPC) and 4-dimethylaminopyridine (DMAP) was found to depend on the pKa of the sulfonamide used. Aryl sulfonamides with pKa ~ 10 gave 4-dimethylamino-pyridinium arylsulfonyl-carbamoylides, while the more acidic heteroa...

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Bibliographic Details
Main Authors: Maria Gdaniec, Jarosław Sączewski, Karolina Lisewska, Agnieszka Kiedrowska, Marta Łobocka, Monika Samsel, Anna Kuchnio, Franciszek Sączewski, Patrick J. Bednarski
Format: Article
Language:English
Published: MDPI AG 2010-02-01
Series:Molecules
Subjects:
Online Access:http://www.mdpi.com/1420-3049/15/3/1113/