Uncovering the active constituents and mechanisms of Rujin Jiedu powder for ameliorating LPS-induced acute lung injury using network pharmacology and experimental investigations

Uncovering the active constituents and mechanisms of Rujin Jiedu powder for ameliorating LPS-induced acute lung injury using network pharmacology and experimental investigations

Background: Acute lung injury (ALI) is a common clinical disease with high mortality. Rujin Jiedu powder (RJJD) has been clinically utilized for the treatment of ALI in China, but the active constituents in RJJD and its protective mechanisms against ALI are still unclear.Methodology: ALI mice were e...

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Bibliographic Details
Main Authors: Yuhui Ma, Hong Xu, Gang Chen, Wei Liu, Chao Ma, Jialei Meng, Lin Yuan, Xu Hua, Guangbo Ge, Ming Lei
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-05-01
Series:Frontiers in Pharmacology
Subjects:
Rujin Jiedu powder (RJJD)
acute lung injury
anti-inflammatory
apoptosis
network pharmacology
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2023.1186699/full

Internet

https://www.frontiersin.org/articles/10.3389/fphar.2023.1186699/full

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