Sex- and age-specific aspects of human peripheral T-cell dynamics

Sex- and age-specific aspects of human peripheral T-cell dynamics

BackgroundThe diversity of the antigenic T cell receptor (TCR) repertoire clonally expressed on T lymphocytes is a key element of the adaptive immune system protective functions. A decline in diversity in the older adults is associated with health deterioration. This diversity is generated by the re...

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Bibliographic Details
Main Authors: Justyna Mika, Kengo Yoshida, Yoichiro Kusunoki, Serge M. Candéias, Joanna Polanska
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-10-01
Series:Frontiers in Immunology
Subjects:
TCR
repertoire diversity
aging
modelling
homeostasis
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2023.1224304/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2023.1224304/full

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