Large-scale discovery of promoter motifs in Drosophila melanogaster.

A key step in understanding gene regulation is to identify the repertoire of transcription factor binding motifs (TFBMs) that form the building blocks of promoters and other regulatory elements. Identifying these experimentally is very laborious, and the number of TFBMs discovered remains relatively...

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Bibliographic Details
Main Authors: Thomas A Down, Casey M Bergman, Jing Su, Tim J P Hubbard
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2007-01-01
Series:PLoS Computational Biology
Online Access:https://doi.org/10.1371/journal.pcbi.0030007