Assessing the Impact of Bedaquiline, Clofazimine, and Linezolid on Mycobacterial Genome Integrity

Assessing the Impact of Bedaquiline, Clofazimine, and Linezolid on Mycobacterial Genome Integrity

Tuberculosis (TB) presents significant medical challenges, largely due to the genetic diversity of <i>Mycobacterium tuberculosis</i>, which enhances the resilience and resistance of the pathogen to first-line treatments. In response to the global rise of drug-resistant TB, second-line an...

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Bibliographic Details
Main Authors: Dániel Molnár, Éva Viola Surányi, Nikoletta Gálik, Judit Tóth, Rita Hirmondó
Format: Article
Language:English
Published: MDPI AG 2024-11-01
Series:Biomolecules
Subjects:
drug resistance
second-line antituberculotics
mycobacteria
genome integrity
DNA repair
Online Access:https://www.mdpi.com/2218-273X/14/11/1451

Internet

https://www.mdpi.com/2218-273X/14/11/1451

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