Disrupted PGR-B and ESR1 signaling underlies defective decidualization linked to severe preeclampsia

Disrupted PGR-B and ESR1 signaling underlies defective decidualization linked to severe preeclampsia

Background: Decidualization of the uterine mucosa drives the maternal adaptation to invasion by the placenta. Appropriate depth of placental invasion is needed to support a healthy pregnancy; shallow invasion is associated with the development of severe preeclampsia (sPE). Maternal contribution to s...

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Bibliografische gegevens
Hoofdauteurs: Tamara Garrido-Gomez, Nerea Castillo-Marco, Mónica Clemente-Ciscar, Teresa Cordero, Irene Muñoz-Blat, Alicia Amadoz, Jorge Jimenez-Almazan, Rogelio Monfort-Ortiz, Reyes Climent, Alfredo Perales-Marin, Carlos Simon
Formaat: Artikel
Taal:English
Gepubliceerd in: eLife Sciences Publications Ltd 2021-10-01
Reeks:eLife
Onderwerpen:
Preeclampsia
human endometrium
decidua
defective decidualization
transcriptomic fingerprint
hormonal receptor
Online toegang:https://elifesciences.org/articles/70753

Internet

https://elifesciences.org/articles/70753

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