Osthole Regulates TGF-β1 and MMP-2/9 Expressions via Activation of PPARα/γ in Cultured Mouse Cardiac Fibroblasts Stimulated with Angiotensin II
PURPOSE. Our previous studies have demonstrated that osthole, an active constituent isolated from the fruit of Cnidium monnieri (L.) Cusson, can prevent isoprenaline-induced myocardial fibrosis in mice, but the underlying mechanism is still unclear. METHODS. The mouse cardiac fibroblasts (CFs) stim...
| Auteurs principaux: | , , |
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| Format: | Article |
| Langue: | English |
| Publié: |
Frontiers Media S.A.
2013-12-01
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| Collection: | Journal of Pharmacy & Pharmaceutical Sciences |
| Accès en ligne: | https://journals.library.ualberta.ca/jpps/index.php/JPPS/article/view/20433 |