Grape seed extract suppresses calcitonin gene-related peptide secretion and upregulates expression of GAD 65/67 and GABAB receptor in primary trigeminal ganglion cultures
The trigeminal ganglion is implicated in the underlying pathology of migraine and temporomandibular joint disorders (TMD), which are orofacial pain conditions involving peripheral and central sensitization. The neuropeptide calcitonin gene-related peptide (CGRP) is synthesized in some trigeminal gan...
Main Authors: | , |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2022-12-01
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Series: | IBRO Neuroscience Reports |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2667242122000586 |