LncRNA MALAT1 silencing protects against cerebral ischemia-reperfusion injury through miR-145 to regulate AQP4

LncRNA MALAT1 silencing protects against cerebral ischemia-reperfusion injury through miR-145 to regulate AQP4

Abstract Background The present study aimed to verify whether long noncoding RNA (lncRNA) MALAT1 is involved in brain tissue damage induced by ischemia-reperfusion injury, and to explore the mechanism by which MALAT1 regulates aquaporin 4 (AQP4). Methods In this study, we established glucose depriva...

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Bibliographic Details
Main Authors: Hongwei Wang, Xiaoxiao Zheng, Jing Jin, Li Zheng, Ting Guan, Yangfan Huo, Shufen Xie, Ying Wu, Wei Chen
Format: Article
Language:English
Published: BMC 2020-03-01
Series:Journal of Biomedical Science
Subjects:
MALAT1
miR-145
Cerebral ischemia-reperfusion injury
AQP4
Online Access:http://link.springer.com/article/10.1186/s12929-020-00635-0

Internet

http://link.springer.com/article/10.1186/s12929-020-00635-0

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