Challenging a bioinformatic tool’s ability to detect microbial contaminants using in silico whole genome sequencing data
High sensitivity methods such as next generation sequencing and polymerase chain reaction (PCR) are adversely impacted by organismal and DNA contaminants. Current methods for detecting contaminants in microbial materials (genomic DNA and cultures) are not sensitive enough and require either a known...
Main Authors: | Nathan D. Olson, Justin M. Zook, Jayne B. Morrow, Nancy J. Lin |
---|---|
Format: | Article |
Language: | English |
Published: |
PeerJ Inc.
2017-09-01
|
Series: | PeerJ |
Subjects: | |
Online Access: | https://peerj.com/articles/3729.pdf |
Similar Items
-
Bioinformatics of genome regulation and structure II /
by: Kolchanov, N. A., et al.
Published: (2006) -
Whole genome sequencing reveals a frameshift mutation and a large deletion in YY1AP1 in a girl with a panvascular artery disease
by: Víctor Raggio, et al.
Published: (2021-05-01) -
The use of whole-genome sequencing and development of bioinformatics to monitor overlapping outbreaks of Candida auris in southern Nevada
by: Andrew Gorzalski, et al.
Published: (2023-07-01) -
Quantitative NMR as a Versatile Tool for the Reference Material Preparation
by: Kihwan Choi, et al.
Published: (2021-01-01) -
Bioinformatics : genomics and post-genomics /
by: Dardel, Frederic, et al.
Published: (2006)