Shared and specific signatures of locomotor ataxia in mutant mice

Shared and specific signatures of locomotor ataxia in mutant mice

Several spontaneous mouse mutants with deficits in motor coordination and associated cerebellar neuropathology have been described. Intriguingly, both visible gait alterations and neuroanatomical abnormalities throughout the brain differ across mutants. We previously used the LocoMouse system to qua...

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Bibliographic Details
Main Authors: Ana S Machado, Hugo G Marques, Diogo F Duarte, Dana M Darmohray, Megan R Carey
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2020-07-01
Series:eLife
Subjects:
locomotion
ataxia
cerebellum
computational ethology
motor coordination
Online Access:https://elifesciences.org/articles/55356

Internet

https://elifesciences.org/articles/55356

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