Multiparity increases the risk of diabetes by impairing the proliferative capacity of pancreatic β cells

Abstract Pregnancy imposes a substantial metabolic burden on women, but little is known about whether or how multiple pregnancies increase the risk of maternal postpartum diabetes. In this study, we assessed the metabolic impact of multiple pregnancies in humans and in a rodent model. Mice that unde...

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Bibliographic Details
Main Authors: Joon Ho Moon, Joonyub Lee, Kyun Hoo Kim, Hyun Jung Kim, Hyeongseok Kim, Hye-Na Cha, Jungsun Park, Hyeonkyu Lee, So-young Park, Hak Chul Jang, Hail Kim
Format: Article
Language:English
Published: Nature Publishing Group 2023-10-01
Series:Experimental and Molecular Medicine
Online Access:https://doi.org/10.1038/s12276-023-01100-2