Albumin-fused thioredoxin ameliorates high-fat diet-induced non-alcoholic steatohepatitis

Albumin-fused thioredoxin ameliorates high-fat diet-induced non-alcoholic steatohepatitis

The pathogenesis of non-alcoholic steatohepatitis (NASH) involves the simultaneous interaction of multiple factors such as lipid accumulation, oxidative stress, and inflammatory response. Here, the effect of human serum albumin (HSA) fused to thioredoxin (Trx) on NASH was investigated. Trx is known...

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Bibliographic Details
Main Authors: Ryota Murata, Hiroshi Watanabe, Ryotaro Iwakiri, Mayuko Chikamatsu, Takao Satoh, Isamu Noguchi, Kengo Yasuda, Ayano Nishinoiri, Takuma Yoshitake, Hiroto Nosaki, Hitoshi Maeda, Toru Maruyama
Format: Article
Language:English
Published: Elsevier 2024-02-01
Series:Heliyon
Subjects:
Albumin fusion
Thioredoxin
Non-alcoholic fatty liver disease
Non-alcoholic steatohepatitis
Oxidative stress
Inflammation
Online Access:http://www.sciencedirect.com/science/article/pii/S2405844024015160

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http://www.sciencedirect.com/science/article/pii/S2405844024015160

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