Combined drug action of 2-phenylimidazo[2,1-b]benzothiazole derivatives on cancer cells according to their oncogenic molecular signatures.

The development of targeted molecular therapies has provided remarkable advances into the treatment of human cancers. However, in most tumors the selective pressure triggered by anticancer agents encourages cancer cells to acquire resistance mechanisms. The generation of new rationally designed targ...

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Bibliographic Details
Main Authors: Alessandro Furlan, Benjamin Roux, Fabienne Lamballe, Filippo Conti, Nathalie Issaly, Fabrice Daian, Jean-François Guillemot, Sylvie Richelme, Magali Contensin, Joan Bosch, Daniele Passarella, Oreste Piccolo, Rosanna Dono, Flavio Maina
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3465283?pdf=render