A Two-Step Mechanism for Creating Stable, Condensed Chromatin with the Polycomb Complex PRC1

The <i>Drosophila</i> PRC1 complex regulates gene expression by modifying histone proteins and chromatin architecture. Two PRC1 subunits, PSC and Ph, are most implicated in chromatin architecture. In vitro, PRC1 compacts chromatin and inhibits transcription and nucleosome remodeling. The...

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Bibliographic Details
Main Authors: Elias Seif, Nicole J. Francis
Format: Article
Language:English
Published: MDPI AG 2024-01-01
Series:Molecules
Subjects:
Online Access:https://www.mdpi.com/1420-3049/29/2/323