A Two-Step Mechanism for Creating Stable, Condensed Chromatin with the Polycomb Complex PRC1

The <i>Drosophila</i> PRC1 complex regulates gene expression by modifying histone proteins and chromatin architecture. Two PRC1 subunits, PSC and Ph, are most implicated in chromatin architecture. In vitro, PRC1 compacts chromatin and inhibits transcription and nucleosome remodeling. The...

Ausführliche Beschreibung

Bibliographische Detailangaben
Hauptverfasser: Elias Seif, Nicole J. Francis
Format: Artikel
Sprache:English
Veröffentlicht: MDPI AG 2024-01-01
Schriftenreihe:Molecules
Schlagworte:
Online Zugang:https://www.mdpi.com/1420-3049/29/2/323