Naturally Acquired Human Immunity to Pneumococcus Is Dependent on Antibody to Protein Antigens.

Naturally acquired immunity against invasive pneumococcal disease (IPD) is thought to be dependent on anti-capsular antibody. However nasopharyngeal colonisation by Streptococcus pneumoniae also induces antibody to protein antigens that could be protective. We have used human intravenous immunoglobu...

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Bibliographic Details
Main Authors: Robert Wilson, Jonathan M Cohen, Mark Reglinski, Ricardo J Jose, Win Yan Chan, Helina Marshall, Corné de Vogel, Stephen Gordon, David Goldblatt, Fernanda C Petersen, Helen Baxendale, Jeremy S Brown
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-01-01
Series:PLoS Pathogens
Online Access:https://doi.org/10.1371/journal.ppat.1006137