Exogenous soluble tumor necrosis factor receptor type I ameliorates murine experimental autoimmune neuritis

Tumor necrosis factor (TNF) and its receptor (TNFR) have been strongly implicated in the pathogenesis of autoimmune disease. Soluble cytokine receptors may be shed naturally from cell membranes to inhibit cytokine activity. Experimental autoimmune neuritis (EAN) is a CD4 Th1 cell-mediated animal mod...

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Bibliographic Details
Main Authors: Lei Bao, J.Urban Lindgren, Yu Zhu, Hans-Gustaf Ljunggren, Jie Zhu
Format: Article
Language:English
Published: Elsevier 2003-02-01
Series:Neurobiology of Disease
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996102000074