The application of CRISPR/Cas9–based genome-wide screening to disease research

High-throughput genetic screening serves as an indispensable approach for deciphering gene functions and the intricate relationships between phenotypes and genotypes. The CRISPR/Cas9 system, with its ability to precisely edit genomes on a large scale, has revolutionized the field by enabling the con...

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Bibliographic Details
Main Authors: Xiuqin Chen, Min Zheng, Su Lin, Meiqing Huang, Shaoying Chen, Shilong Chen
Format: Article
Language:English
Published: Elsevier 2025-02-01
Series:Molecular and Cellular Probes
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S0890850824000562