Characterization of the Venom of C. d. cumanesis of Colombia: Proteomic Analysis and Antivenomic Study

Characterization of the Venom of C. d. cumanesis of Colombia: Proteomic Analysis and Antivenomic Study

The Colombian rattlesnake Crotalus durissus cumanensis is distributed in three geographic zones of the country: the Atlantic Coast, the upper valley of the Magdalena River, and the eastern plains of the Colombian Orinoquía. Its venom induces neurological symptoms, such as eyelid ptosis, myasthenic f...

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Bibliographic Details
Main Authors: Juan Carlos Quintana-Castillo, Leidy Johana Vargas, Cesar Segura, Sebastián Estrada-Gómez, Julio César Bueno-Sánchez, Juan Carlos Alarcón
Format: Article
Language:English
Published: MDPI AG 2018-02-01
Series:Toxins
Subjects:
C. d. cumanensis venom
antivenom
HPLC-nESI-MS/MS
peptide identification
Key Contribution
This work carried out a proteomic analysis of C. d. cumanensis from Colombia by using HPLC-nESI MS/MS and subsequently was evaluated the effect of a commercial antivenom against the venom
Online Access:http://www.mdpi.com/2072-6651/10/2/85

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http://www.mdpi.com/2072-6651/10/2/85

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