A Novel Mapping Strategy Utilizing Mouse Chromosome Substitution Strains Identifies Multiple Epistatic Interactions That Regulate Complex Traits
The genetic contribution of additive vs. non-additive (epistatic) effects in the regulation of complex traits is unclear. While genome-wide association studies typically ignore gene-gene interactions, in part because of the lack of statistical power for detecting them, mouse chromosome substitution...
| Հիմնական հեղինակներ: | , , , , , |
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| Ձևաչափ: | Հոդված |
| Լեզու: | English |
| Հրապարակվել է: |
Oxford University Press
2020-12-01
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| Շարք: | G3: Genes, Genomes, Genetics |
| Խորագրեր: | |
| Առցանց հասանելիություն: | http://g3journal.org/lookup/doi/10.1534/g3.120.401824 |