An allele-selective inter-chromosomal protein bridge supports monogenic antigen expression in the African trypanosome

An allele-selective inter-chromosomal protein bridge supports monogenic antigen expression in the African trypanosome

Abstract UPF1-like helicases play roles in telomeric heterochromatin formation and X-chromosome inactivation, and also in monogenic variant surface glycoprotein (VSG) expression via VSG exclusion-factor-2 (VEX2), a UPF1-related protein in the African trypanosome. We show that VEX2 associates with ch...

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Bibliographic Details
Main Authors: Joana R. C. Faria, Michele Tinti, Catarina A. Marques, Martin Zoltner, Harunori Yoshikawa, Mark C. Field, David Horn
Format: Article
Language:English
Published: Nature Portfolio 2023-12-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-023-44043-y

Internet

https://doi.org/10.1038/s41467-023-44043-y

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