Screening for sickle cell disease in newborns: a systematic review

Screening for sickle cell disease in newborns: a systematic review

Abstract Background Sickle cell disease (SCD) is an inherited autosomal recessive disorder caused by the replacement of normal haemoglobin (HbA) by mutant Hb (sickle Hb, HbS). The sickle-shaped red blood cells lead to haemolysis and vaso-occlusion. Especially in the first years of life, patients wit...

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Bibliographic Details
Main Authors: Britta Runkel, Birgit Klüppelholz, Anne Rummer, Wiebke Sieben, Ulrike Lampert, Claudia Bollig, Martina Markes, Ulrike Paschen, Konstanze Angelescu
Format: Article
Language:English
Published: BMC 2020-10-01
Series:Systematic Reviews
Subjects:
Newborn screening
Anaemia—sickle cell
SCD screening
Systematic review
Online Access:http://link.springer.com/article/10.1186/s13643-020-01504-5

Internet

http://link.springer.com/article/10.1186/s13643-020-01504-5

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