Dihydromyricetin Alleviates Pulmonary Fibrosis by Regulating Abnormal Fibroblasts Through the STAT3/p-STAT3/GLUT1 Signaling Pathway

Dihydromyricetin Alleviates Pulmonary Fibrosis by Regulating Abnormal Fibroblasts Through the STAT3/p-STAT3/GLUT1 Signaling Pathway

Background: Idiopathic pulmonary fibrosis (IPF) is a chronic and progressive disorder with a poor prognosis. Although dihydromyricetin (DHM), extracted from vine tea and other Ampelopsis species, has been proven to have anti-inflammatory and antioxidant functions, the effects of DHM on IPF remain un...

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Bibliographic Details
Main Authors: Zhen Li, Jing Geng, Bingbing Xie, Jiarui He, Jing Wang, Liang Peng, Yinan Hu, Huaping Dai, Chen Wang
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-03-01
Series:Frontiers in Pharmacology
Subjects:
idiopathic pulmonary fibrosis
dihydromyricetin
fibroblast
myofibroblast
GLUT1
glucose metabolism
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2022.834604/full

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https://www.frontiersin.org/articles/10.3389/fphar.2022.834604/full

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